(Anti-pDC/activated B cell antibody)
SBI-3150 is an antibody drug candidate that can target both pDCs and B cells activated in various autoimmune diseases. Although an antibody drug targeting B cells is already marketed and shows efficacy,SBI-3150 has potential to show less side effects and higher efficacy as a therapeutic drug for autoimmune diseases since it can specifically target activated B cells which play important role in these therapeutic pathway.
Mode of action
SBI-3150 is an antibody against a target specifically expressed on both pDCs and activated
B cells.The antibody binds to pDCs producing large amount of IFNα and activated
B cells producing autoantibody.It can be applied to autoimmune diseases by killing
pDC and activated B cells simultaneously.
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Direct to Research & Development Dept.